After just 3 treatments over 12 weeks, this patient experienced visible regrowth, reduced scalp inflammation, and healthier hair density.
Hair loss is rarely just a “hair problem.” In this case, our patient presented with advanced hair loss marked by a substantial bald patch at the back of the scalp near the base of the neck — an area that later showed visible regrowth after treatment, along with thinning along the sides of the scalp. The pattern and severity were consistent with androgenic alopecia, compounded by visible scalp inflammation and follicle miniaturization.
What Was Contributing to Her Hair Loss
A deeper evaluation revealed that her hair loss was multifactorial, not simply cosmetic:
- Hormonal mismanagement
Her hormones had been previously mismanaged, with inadequate estrogen and progesterone support and elevated adrenal androgens (high DHEA-S). In women, elevated DHEA-S can increase androgen signaling at the scalp, accelerating follicle miniaturization and progressive thinning. - Elevated homocysteine
Her homocysteine levels were also elevated, reflecting impaired methylation and increased oxidative stress. Elevated homocysteine can negatively impact circulation, oxygen delivery, and nutrient flow to hair follicles, making it difficult for hair to remain in the growth phase. - Scalp inflammation
Chronic low-grade inflammation around the hair follicle disrupts the normal growth cycle and contributes to ongoing shedding. - Loss of follicle signaling
Stressed or aging follicles often lose the cellular communication needed to stay in the active growth (anagen) phase.
Topical products alone would not have addressed these underlying drivers.
Our Approach: PRP + Exosomes + Internal Optimization
To address both the local scalp environment and the internal contributors, we implemented a combined regenerative strategy:
✨ Hair PRP + Exosome Therapy
- Platelet-Rich Plasma (PRP) was used to deliver concentrated growth factors that stimulate dormant follicles, improve circulation, and support tissue repair.
- Exosomes were added to enhance cellular communication, calm inflammation, and amplify follicular regeneration beyond what PRP alone can achieve.
Treatments were performed over 12 weeks (3 sessions).
⚖️ Hormone & Metabolic Optimization
At the same time, we corrected internal factors that were actively contributing to hair loss:
- Addressing elevated DHEA-S and androgen signaling
- Supporting estrogen and progesterone appropriately
- Improving methylation and lowering homocysteine to support circulation and follicle health
This internal optimization is critical — hair follicles cannot regenerate optimally if hormonal and metabolic signals are working against them.
The Results
After three treatments:
- Visible regrowth in the large bald area at the back of the scalp
- Improved density along the sides
- Reduced scalp redness and inflammation
- Healthier overall hair texture and scalp environment
These changes occurred within just 12 weeks, highlighting the power of regenerative therapies when paired with proper internal support.
Why This Matters
This case highlights an important truth:
👉 Successful hair restoration requires both regenerative treatment and internal balance.
PRP and exosomes help repair and reactivate follicles — but elevated androgens, impaired methylation, and hormone mismanagement can sabotage results if left unaddressed, especially in female androgenic alopecia.
Photos shown reflect real patient results after 3 PRP + exosome treatments over 12 weeks. Individual results may vary.
- Before:Significant hair loss with a large bald area at the back of the scalp near the base of the neck, an area no longer responding to topical treatments.
- After (12 weeks): Visible regrowth and improved scalp coverage following 3 PRP + exosome treatments with hormone optimization.
